{"id":9764,"date":"2025-02-25T16:48:55","date_gmt":"2025-02-25T15:48:55","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=9764"},"modified":"2025-02-25T16:48:55","modified_gmt":"2025-02-25T15:48:55","slug":"instantania-caixaresearch-els-adipocits-els-nostres-aliats-davant-dun-exces-de-calories","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-els-adipocits-els-nostres-aliats-davant-dun-exces-de-calories\/","title":{"rendered":"Instant\u00e0nia CaixaResearch: els adip\u00f2cits, els nostres aliats davant d\u2019un exc\u00e9s de calories"},"content":{"rendered":"

\"\"<\/p>\n

Fa milers d\u2019anys, trobar aliments no era una tasca f\u00e0cil i el nostre cos es va especialitzar cada vegada m\u00e9s a emmagatzemar aquest recurs energ\u00e8tic tan preuat: el greix.\u00a0<\/span><\/p>\n

Ara, la realitat \u00e9s tota una altra. En la societat actual, caracteritzada pel sedentarisme i les dietes riques en calories, acumulem greix molt r\u00e0pidament i l\u2019exc\u00e9s de greix al nostre organisme est\u00e0 directament relacionat amb l\u2019obesitat i altres problemes de salut metab\u00f2lica<\/strong>.\u00a0<\/span><\/p>\n

Quan ingerim calories en exc\u00e9s, unes c\u00e8l\u00b7lules anomenades <\/span>adip\u00f2cits<\/i><\/strong> s\u2019encarreguen d\u2019emmagatzemar-les en forma de greix<\/strong>. D\u2019aquesta manera eviten que el greix es dipositi en altres teixits i \u00f2rgans<\/strong> com el fetge o les parets dels vasos sanguinis, cosa que generaria toxicitat. Fins ara no se sabia b\u00e9 com aconseguien acumular-la sense veure\u2019s desbordats, per\u00f2 recentment un equip del Centro Nacional de Investigaciones Cardiovasculares<\/strong> (<\/span>CNIC<\/span><\/a>) liderat per l\u2019investigador de la xarxa CaixaResearch <\/span>Miguel \u00c1ngel del Pozo<\/span><\/a> n\u2019ha trobat la clau.\u00a0<\/span><\/p>\n

El seu estudi, <\/span>publicat a <\/span>Nature Communications<\/span><\/i><\/a>, descriu el mecanisme que permet als adip\u00f2cits expandir-se de manera segura. Ho fan gr\u00e0cies a les cav\u00e8oles, uns petits plecs a la membrana cel\u00b7lular<\/strong> que actuen com a sensors i amortidors de les tensions generades per l\u2019acumulaci\u00f3 de greix.\u00a0<\/span><\/p>\n

\u00abQuan l\u2019adip\u00f2cit s\u2019omple de greix, les cav\u00e8oles s\u2019aplanen per ajudar-lo a cr\u00e9ixer i a acumular molts m\u00e9s l\u00edpids sense trencar-se\u00bb, explica Del Pozo. Aix\u00ed eviten d\u2019alliberar el greix a l\u2019organisme<\/strong>, cosa que generaria inflamacions i alteracions metab\u00f2liques.\u00a0<\/span><\/p>\n

Els resultats de l\u2019estudi suposen un gran avan\u00e7 en la comprensi\u00f3 de les malalties metab\u00f2liques i obren la porta al desenvolupament de noves estrat\u00e8gies terap\u00e8utiques<\/strong> per combatre els trastorns relacionats amb l\u2019exc\u00e9s energ\u00e8tic cr\u00f2nic, com el sobrep\u00e8s, l\u2019obesitat, la lipodistr\u00f2fia o la s\u00edndrome metab\u00f2lica. A m\u00e9s, aquest descobriment aporta llum sobre els mecanismes que regulen l\u2019acumulaci\u00f3 de greix<\/strong> i podria ajudar a entendre per qu\u00e8 la salut metab\u00f2lica varia entre persones amb dip\u00f2sits de greix similars.\u00a0<\/span><\/p>\n

T\u2019expliquem m\u00e9s coses sobre aquest estudi en el fil de X seg\u00fcent<\/strong>.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"<\/p>\n

Fa milers d\u2019anys, trobar aliments no era una tasca f\u00e0cil i el nostre cos es va especialitzar cada vegada m\u00e9s a emmagatzemar aquest recurs energ\u00e8tic tan preuat: el greix.\u00a0<\/p>\n

Ara, la realitat \u00e9s tota una altra. En la societat actual, caracteritzada pel sedentarisme i les dietes riques en calories, acumulem greix molt r\u00e0pidament i l\u2019exc\u00e9s de greix al nostre organisme est\u00e0 directament relacionat amb l\u2019obesitat i altres problemes de salut metab\u00f2lica.\u00a0<\/p>\n

Quan ingerim calories en exc\u00e9s, unes c\u00e8l\u00b7lules anomenades adip\u00f2cits<\/i> s\u2019encarreguen d\u2019emmagatzemar-les en forma de greix. D\u2019aquesta manera eviten que el greix es dipositi en altres teixits i \u00f2rgans com el fetge o les parets dels vasos sanguinis,<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[340],"tags":[],"class_list":["post-9764","post","type-post","status-publish","format-standard","hentry","category-sense-categoria"],"acf":[],"yoast_head":"\nInstant\u00e0nia CaixaResearch: els adip\u00f2cits, els nostres aliats davant d\u2019un exc\u00e9s de calories - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-els-adipocits-els-nostres-aliats-davant-dun-exces-de-calories\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instant\u00e0nia CaixaResearch: els adip\u00f2cits, els nostres aliats davant d\u2019un exc\u00e9s de calories - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Fa milers d\u2019anys, trobar aliments no era una tasca f\u00e0cil i el nostre cos es va especialitzar cada vegada m\u00e9s a emmagatzemar aquest recurs energ\u00e8tic tan preuat: el greix.\u00a0 Ara, la realitat \u00e9s tota una altra. En la societat actual, caracteritzada pel sedentarisme i les dietes riques en calories, acumulem greix molt r\u00e0pidament i l\u2019exc\u00e9s de greix al nostre organisme est\u00e0 directament relacionat amb l\u2019obesitat i altres problemes de salut metab\u00f2lica.\u00a0 Quan ingerim calories en exc\u00e9s, unes c\u00e8l\u00b7lules anomenades adip\u00f2cits s\u2019encarreguen d\u2019emmagatzemar-les en forma de greix. 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