{"id":8398,"date":"2024-05-31T08:15:54","date_gmt":"2024-05-31T07:15:54","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=8398"},"modified":"2024-05-31T09:11:24","modified_gmt":"2024-05-31T08:11:24","slug":"instantania-caixaresearch-nou-marcador-per-avaluar-lefectivitat-de-la-terapia-contra-el-cancer-de-prostata-metastatic","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-nou-marcador-per-avaluar-lefectivitat-de-la-terapia-contra-el-cancer-de-prostata-metastatic\/","title":{"rendered":"Instant\u00e0nia CaixaResearch: Nou marcador per avaluar l\u2019efectivitat de la ter\u00e0pia contra el c\u00e0ncer de pr\u00f2stata metast\u00e0tic"},"content":{"rendered":"

\"\"<\/p>\n

<\/h3>\n

En qu\u00e8 es basen els metges per proposar un tractament contra el c\u00e0ncer o un altre? Com determinen quin \u00e9s el m\u00e9s adequat per a cada pacient?\u00a0<\/b><\/em><\/h3>\n

Per avaluar com responen els pacients a les ter\u00e0pies, els experts fan servir de manera estandarditzada <\/span>els criteris RECIST<\/b> (Response Evaluation Criteria in Solid Tumors). <\/span>Aquest m\u00e8tode permet avaluar si els tumors es redueixen, estan igual o creixen, utilitzant proves d\u2019imatge com la tomografia computada (TC). Tot i que l\u2019aplicaci\u00f3 d\u2019aquests criteris ha millorat les taxes de superviv\u00e8ncia en oncologia i \u00e9s molt \u00fatil per estudiar la resposta de tumors s\u00f2lids, <\/span>no permet avaluar adequadament la resposta en pacients amb met\u00e0stasi en certes localitzacions, com l\u2019esquelet<\/b>.\u00a0<\/span><\/p>\n

Un exemple de les limitacions dels criteris RECIST s\u2019observa en el c\u00e0ncer de pr\u00f2stata<\/b>, en qu\u00e8 les met\u00e0stasis \u00f2ssies, que s\u00f3n freq\u00fcents, afecten entre el 8 i el 35\u00a0% dels casos en el moment del diagn\u00f2stic, i fins el 75\u00a0% dels c\u00e0ncers en estadis avan\u00e7ats.\u00a0<\/span><\/p>\n

Fa poc, el grup de Radi\u00f2mica del Vall d\u2019Hebron Institut d\u2019Oncologia (VHIO), liderat per la investigadora Raquel L\u00f3pez-P\u00e9rez, de la xarxa CaixaResearch, va publicar a la <\/span>revista <\/span>European Urology<\/span><\/i><\/a> un nou marcador de resposta als tractaments en pacients amb c\u00e0ncer de pr\u00f2stata metast\u00e0tic ossi<\/b>.\u00a0<\/span><\/p>\n

Mitjan\u00e7ant t\u00e8cniques de resson\u00e0ncia magn\u00e8tica, els investigadors van identificar que, en casos de met\u00e0stasis \u00f2ssies, <\/span>la disminuci\u00f3 del volum de c\u00e8l\u00b7lules cancer\u00edgenes associada a l\u2019augment de la quantitat de greix dins dels ossos \u00e9s indicador d\u2019una resposta positiva al tractament<\/b>.\u00a0<\/span><\/p>\n

Aquest descobriment representa un aven\u00e7 significatiu en el m\u00e8tode d\u2019avaluaci\u00f3 de la resposta als tractaments basat en RECIST i<\/span> marca un pas endavant en el pron\u00f2stic i el tractament de les met\u00e0stasis<\/b>. <\/span>La capacitat de predir la resposta r\u00e0pidament i ajustar l\u2019estrat\u00e8gia terap\u00e8utica pot suposar una gran difer\u00e8ncia per als pacients.<\/b> T\u2019expliquem m\u00e9s coses sobre aquest estudi en el <\/span>fil de X<\/b> seg\u00fcent: <\/span>Enlla\u00e7 al fil X<\/em><\/a>.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"<\/p>\n

En qu\u00e8 es basen els metges per proposar un tractament contra el c\u00e0ncer o un altre? Com determinen quin \u00e9s el m\u00e9s adequat per a cada pacient?\u00a0<\/em><\/p>\n

Per avaluar com responen els pacients a les ter\u00e0pies, els experts fan servir de manera estandarditzada els criteris RECIST (Response Evaluation Criteria in Solid Tumors). Aquest m\u00e8tode permet avaluar si els tumors es redueixen, estan igual o creixen, utilitzant proves d\u2019imatge com la tomografia computada (TC). Tot i que l\u2019aplicaci\u00f3 d\u2019aquests criteris ha millorat les taxes de superviv\u00e8ncia en oncologia i \u00e9s molt \u00fatil per estudiar la resposta de tumors s\u00f2lids, no permet avaluar adequadament la resposta en pacients amb met\u00e0stasi en certes localitzacions,<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[520,519,340],"tags":[],"class_list":["post-8398","post","type-post","status-publish","format-standard","hentry","category-divulgacio-cientifica","category-investigacio","category-sense-categoria"],"acf":[],"yoast_head":"\nInstant\u00e0nia CaixaResearch: Nou marcador per avaluar l\u2019efectivitat de la ter\u00e0pia contra el c\u00e0ncer de pr\u00f2stata metast\u00e0tic - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-nou-marcador-per-avaluar-lefectivitat-de-la-terapia-contra-el-cancer-de-prostata-metastatic\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instant\u00e0nia CaixaResearch: Nou marcador per avaluar l\u2019efectivitat de la ter\u00e0pia contra el c\u00e0ncer de pr\u00f2stata metast\u00e0tic - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"En qu\u00e8 es basen els metges per proposar un tractament contra el c\u00e0ncer o un altre? 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