{"id":8315,"date":"2024-04-29T09:25:57","date_gmt":"2024-04-29T08:25:57","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=8315"},"modified":"2024-04-29T12:04:56","modified_gmt":"2024-04-29T11:04:56","slug":"instantania-caixaresearch-abril-24","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-abril-24\/","title":{"rendered":"Instant\u00e0nia CaixaResearch"},"content":{"rendered":"

\"\"<\/span><\/p>\n

Totes les c\u00e8l\u00b7lules del cos hum\u00e0 comparteixen els mateixos gens; tanmateix, la manera en qu\u00e8 aquests gens s\u2019expressen varia entre els diferents tipus cel\u00b7lulars: entre d\u2019altres, les neurones, les c\u00e8l\u00b7lules sangu\u00ednies o les que formen els m\u00fasculs. Aquesta variabilitat en l\u2019expressi\u00f3 \u00e9s la que confereix a <\/span>cada c\u00e8l\u00b7lula una identitat \u00fanica i determina tant l\u2019estructura com les funcions que t\u00e9 al llarg de la vida<\/b>. I com aconsegueixen les c\u00e8l\u00b7lules mantenir aquesta identitat al llarg del temps?<\/span><\/p>\n

L\u2019equip liderat per l\u2019<\/span>investigador CaixaResearch \u00c1ngel Barco<\/b><\/a>, <\/span>de l\u2019Instituto de Neurociencias CSIC-UMH<\/b> d\u2019Alacant, ha identificat <\/span>el paper crucial de la prote\u00efna Kdm1a en la conservaci\u00f3 de la identitat neuronal<\/b>. Els resultats del seu estudi, publicats a <\/span>Nature communications<\/span><\/i>, demostren que l\u2019eliminaci\u00f3 de Kdm1a altera l\u2019expressi\u00f3 g\u00e8nica de les neurones, la qual cosa condueix, al seu torn, al mal funcionament d\u2019aquestes c\u00e8l\u00b7lules.<\/span><\/p>\n

Les alteracions associades a la manca de Kdm1a no sols s\u2019han relacionat amb el desenvolupament d\u2019algunes malalties rares, sin\u00f3 tamb\u00e9 amb el proc\u00e9s natural d\u2019envelliment.<\/b> Aquest descobriment representa un avan\u00e7 significatiu cap a una millor comprensi\u00f3 d\u2019aquestes patologies i obre noves perspectives per al desenvolupament de tractaments que endarrereixin la p\u00e8rdua de capacitats cognitives associada a l\u2019edat.<\/span><\/p>\n

Aprofundeix en aquest estudi al <\/span>fil de X<\/b> seg\u00fcent: <\/span>Enlla\u00e7 fil X<\/a>.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"<\/p>\n

Totes les c\u00e8l\u00b7lules del cos hum\u00e0 comparteixen els mateixos gens; tanmateix, la manera en qu\u00e8 aquests gens s\u2019expressen varia entre els diferents tipus cel\u00b7lulars: entre d\u2019altres, les neurones, les c\u00e8l\u00b7lules sangu\u00ednies o les que formen els m\u00fasculs. Aquesta variabilitat en l\u2019expressi\u00f3 \u00e9s la que confereix a cada c\u00e8l\u00b7lula una identitat \u00fanica i determina tant l\u2019estructura com les funcions que t\u00e9 al llarg de la vida. I com aconsegueixen les c\u00e8l\u00b7lules mantenir aquesta identitat al llarg del temps?<\/p>\n

L\u2019equip liderat per l\u2019investigador CaixaResearch \u00c1ngel Barco<\/a>, de l\u2019Instituto de Neurociencias CSIC-UMH d\u2019Alacant, ha identificat el paper crucial de la prote\u00efna Kdm1a en la conservaci\u00f3 de la identitat neuronal. Els resultats del seu estudi,<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[520,340],"tags":[],"class_list":["post-8315","post","type-post","status-publish","format-standard","hentry","category-divulgacio-cientifica","category-sense-categoria"],"acf":[],"yoast_head":"\nInstant\u00e0nia CaixaResearch - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-abril-24\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instant\u00e0nia CaixaResearch - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Totes les c\u00e8l\u00b7lules del cos hum\u00e0 comparteixen els mateixos gens; tanmateix, la manera en qu\u00e8 aquests gens s\u2019expressen varia entre els diferents tipus cel\u00b7lulars: entre d\u2019altres, les neurones, les c\u00e8l\u00b7lules sangu\u00ednies o les que formen els m\u00fasculs. Aquesta variabilitat en l\u2019expressi\u00f3 \u00e9s la que confereix a cada c\u00e8l\u00b7lula una identitat \u00fanica i determina tant l\u2019estructura com les funcions que t\u00e9 al llarg de la vida. I com aconsegueixen les c\u00e8l\u00b7lules mantenir aquesta identitat al llarg del temps? L\u2019equip liderat per l\u2019investigador CaixaResearch \u00c1ngel Barco, de l\u2019Instituto de Neurociencias CSIC-UMH d\u2019Alacant, ha identificat el paper crucial de la prote\u00efna Kdm1a en la conservaci\u00f3 de la identitat neuronal. 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Aquesta variabilitat en l\u2019expressi\u00f3 \u00e9s la que confereix a cada c\u00e8l\u00b7lula una identitat \u00fanica i determina tant l\u2019estructura com les funcions que t\u00e9 al llarg de la vida. I com aconsegueixen les c\u00e8l\u00b7lules mantenir aquesta identitat al llarg del temps? L\u2019equip liderat per l\u2019investigador CaixaResearch \u00c1ngel Barco, de l\u2019Instituto de Neurociencias CSIC-UMH d\u2019Alacant, ha identificat el paper crucial de la prote\u00efna Kdm1a en la conservaci\u00f3 de la identitat neuronal. 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