{"id":8215,"date":"2024-03-22T12:28:40","date_gmt":"2024-03-22T11:28:40","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=8215"},"modified":"2024-03-22T12:28:44","modified_gmt":"2024-03-22T11:28:44","slug":"instantania-caixaresearch-un-nou-capitol-en-la-investigacio-del-cancer","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-un-nou-capitol-en-la-investigacio-del-cancer\/","title":{"rendered":"Instant\u00e0nia CaixaResearch: Un nou cap\u00edtol en la investigaci\u00f3 del c\u00e0ncer"},"content":{"rendered":"

\"\"<\/span><\/p>\n

Un equip internacional d\u2019investigadors, coliderat per la <\/span>investigadora de la xarxa CaixaResearch<\/b><\/a> Ana Janic<\/b>, del Departament de Medicina i Ci\u00e8ncies de la Vida de la Universitat Pompeu Fabra (MELIS-UPF), i per cient\u00edfics del Walter and Eliza Hall Institute (WEHI), a Melbourne, <\/span>ha revelat el paper essencial del gen ZMAT3 com a supressor tumoral<\/b>.<\/span><\/p>\n

El c\u00e0ncer es presenta quan les c\u00e8l\u00b7lules es multipliquen sense control i es disseminen a altres teixits o \u00f2rgans. Per contrarestar aquesta proliferaci\u00f3 anormal, <\/span>les nostres c\u00e8l\u00b7lules disposen de diversos mecanismes de defensa, entre els quals destaquen els gens supressors de tumors<\/b>. Gens com el <\/span>p53<\/b>, conegut com \u00ab<\/span>el guardi\u00e0 del genoma<\/b>\u00bb, exerceix un paper crucial en aquest proc\u00e9s. De fet, <\/span>la meitat dels c\u00e0ncers del m\u00f3n estan relacionats amb mutacions d\u2019aquest gen<\/b>.<\/span><\/p>\n

L\u2019estudi, publicat a <\/span>Cell Death and Differentiation<\/span><\/i><\/a>, ha revelat que el gen ZMAT3 exerceix un paper crucial en el funcionament correcte del gen p53. <\/span>Aquesta interacci\u00f3 s\u2019ha relacionat amb la prevenci\u00f3 d\u2019alguns tipus de c\u00e0ncer, incloent-hi limfomes, leuc\u00e8mies i altres c\u00e0ncers diversos.<\/b><\/p>\n

Aquest descobriment no sols ajuda a <\/span>entendre millor la complexitat de la biologia cel\u00b7lular del c\u00e0ncer<\/b>, sin\u00f3 que tamb\u00e9 podria repercutir en el <\/span>disseny de futures estrat\u00e8gies per desenvolupar ter\u00e0pies m\u00e9s eficaces<\/b> per tractar el c\u00e0ncer.<\/span>T\u2019ho expliquem en aquest fil<\/a> amb la nova Instant\u00e0nia CaixaResearch.<\/span>
\n<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"<\/p>\n

Un equip internacional d\u2019investigadors, coliderat per la investigadora de la xarxa CaixaResearch<\/a> Ana Janic, del Departament de Medicina i Ci\u00e8ncies de la Vida de la Universitat Pompeu Fabra (MELIS-UPF), i per cient\u00edfics del Walter and Eliza Hall Institute (WEHI), a Melbourne, ha revelat el paper essencial del gen ZMAT3 com a supressor tumoral.<\/p>\n

El c\u00e0ncer es presenta quan les c\u00e8l\u00b7lules es multipliquen sense control i es disseminen a altres teixits o \u00f2rgans. Per contrarestar aquesta proliferaci\u00f3 anormal, les nostres c\u00e8l\u00b7lules disposen de diversos mecanismes de defensa, entre els quals destaquen els gens supressors de tumors. Gens com el p53, conegut com \u00abel guardi\u00e0 del genoma\u00bb, exerceix un paper crucial en aquest proc\u00e9s.<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[520,340],"tags":[],"class_list":["post-8215","post","type-post","status-publish","format-standard","hentry","category-divulgacio-cientifica","category-sense-categoria"],"acf":[],"yoast_head":"\nInstant\u00e0nia CaixaResearch: Un nou cap\u00edtol en la investigaci\u00f3 del c\u00e0ncer - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-un-nou-capitol-en-la-investigacio-del-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instant\u00e0nia CaixaResearch: Un nou cap\u00edtol en la investigaci\u00f3 del c\u00e0ncer - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Un equip internacional d\u2019investigadors, coliderat per la investigadora de la xarxa CaixaResearch Ana Janic, del Departament de Medicina i Ci\u00e8ncies de la Vida de la Universitat Pompeu Fabra (MELIS-UPF), i per cient\u00edfics del Walter and Eliza Hall Institute (WEHI), a Melbourne, ha revelat el paper essencial del gen ZMAT3 com a supressor tumoral. 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