{"id":2445,"date":"2014-07-30T00:00:00","date_gmt":"2014-07-30T00:00:00","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=2445"},"modified":"2020-04-30T09:10:32","modified_gmt":"2020-04-30T09:10:32","slug":"un-xip-permetra-detectar-el-cancer-de-manera-precoc","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/un-xip-permetra-detectar-el-cancer-de-manera-precoc\/","title":{"rendered":"Un xip permetr\u00e0 detectar el c\u00e0ncer de manera preco\u00e7"},"content":{"rendered":"

<\/p>\n

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Per Montserrat Capdevila Freixas<\/strong>, \u00c0rea de Ci\u00e8ncia i Medi Ambient de l’Obra Social “la Caixa”.<\/span><\/p>\n

Actualment, la major part dels c\u00e0ncers es detecten a nivell macrosc\u00f2pic, una vegada que el tumor ja est\u00e0 format per milions de c\u00e8l\u00b7lules canceroses i la malaltia comen\u00e7a a avan\u00e7ar cap a una fase m\u00e9s madura. Aquesta \u00e9s la situaci\u00f3 actual, per\u00f2 qu\u00e8 passaria si pogu\u00e9ssim diagnosticar el c\u00e0ncer abans que estigu\u00e9s en una fase tan avan\u00e7ada? Seria com intentar apagar un incendi a casa quan nom\u00e9s hi ha unes poques espurnes o fer-ho amb un incendi que ha pres i s’escampa de manera imparable per diferents habitacions.<\/span><\/p>\n

Un equip d’investigadors de diversos pa\u00efsos, coordinat pel prof. Romain Quidant de l’Institut de Ci\u00e8ncies Fot\u00f2niques (ICFO)<\/a>, va anunciar recentment el desenvolupament d’una plataforma de lab-on-a-chip<\/a>, un nanodispositiu capa\u00e7 de detectar marcadors de prote\u00efnes de c\u00e0ncer a la sang utilitzant els \u00faltims aven\u00e7os en fot\u00f2nica, microfluids, nanofabricaci\u00f3 i qu\u00edmica de superf\u00edcies. Aquest dispositiu t\u00e9 la capacitat de detectar concentracions molt baixes d’aquestes prote\u00efnes marcadores de c\u00e0ncer a la sang, de manera que permet el diagn\u00f2stic de la malaltia en una etapa preco\u00e7, cosa que \u00e9s clau per al diagn\u00f2stic i el tractament encertat d’aquesta malaltia.<\/p>\n

Aquest nanodispositiu mostra un gran potencial per a tractaments futurs de c\u00e0ncer a causa de la seva fiabilitat, sensibilitat, baix cost i f\u00e0cil portabilitat. Aix\u00f2 permetr\u00e0 millorar el diagn\u00f2stic i definir els tractaments m\u00e9s indicats en llocs remots amb dificultats d’acc\u00e9s a hospitals i cl\u00edniques m\u00e8diques.<\/p>\n

Com funciona el xip?<\/strong><\/p>\n

El dispositiu \u00e9s extremadament compacte i allotja diversos sensors distribu\u00efts en una xarxa de microcanals de fluids que permet dur a terme m\u00faltiples an\u00e0lisis. Al seu torn, una s\u00e8rie de nanopart\u00edcules d’or implantades a la superf\u00edcie del xip i programades qu\u00edmicament amb un receptor d’antic\u00f2s s\u00f3n capaces d’atreure espec\u00edficament els marcadors de prote\u00efnes que circulen a la sang. Quan s’injecta una gota de sang al xip, la sang circula a trav\u00e9s dels microcanals i si hi ha marcadors de c\u00e0ncer, en passar pels microcanals, aquests s’adhereixen a les nanopart\u00edcules, cosa que provoca una s\u00e8rie de canvis. El dispositiu, capa\u00e7 de supervisar en q\u00fcesti\u00f3 de minuts la magnitud d’aquests canvis directament relacionats amb la concentraci\u00f3 de marcadors a la sang del pacient, proporciona una avaluaci\u00f3 directa del risc per al pacient de desenvolupar un c\u00e0ncer.<\/p>\n

Top Ci\u00e8ncia, ci\u00e8ncia puntera<\/strong><\/p>\n

La t\u00e8cnica desenvolupada al nanodispositiu tamb\u00e9 podria servir per detectar la pres\u00e8ncia del VIH a la sang, segons una investigaci\u00f3 que actualment duen a terme conjuntament l’ICFO i IrsiCaixa<\/a>. Precisament a la instal\u00b7laci\u00f3 Top Ci\u00e8ncia<\/a>, de CosmoCaixa<\/a>, espai destinat al foment de vocacions cient\u00edfiques i a la trobada amb la investigaci\u00f3 m\u00e9s actual, es pot con\u00e8ixer investigaci\u00f3 i d’altres tant de l’ICFO com d’IrsiCaixa. Gr\u00e0cies a aquesta instal\u00b7laci\u00f3, l’Obra Social “la Caixa”<\/a> acosta els projectes cient\u00edfics m\u00e9s actuals a la ciutadania i mostra la import\u00e0ncia que t\u00e9 la ci\u00e8ncia per a la societat.<\/p>\n

M\u00e9s informaci\u00f3<\/strong><\/span><\/div>\n
V\u00eddeo: Com funciona el SPEDOC lab-on-a-chip<\/a><\/span><\/div>\n<\/p><\/div>\n

<\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<\/p>\n

Per Montserrat Capdevila Freixas, \u00c0rea de Ci\u00e8ncia i Medi Ambient de l’Obra Social “la Caixa”.<\/p>\n

Actualment, la major part dels c\u00e0ncers es detecten a nivell macrosc\u00f2pic, una vegada que el tumor ja est\u00e0 format per milions de c\u00e8l\u00b7lules canceroses i la malaltia comen\u00e7a a avan\u00e7ar cap a una fase m\u00e9s madura. Aquesta \u00e9s la situaci\u00f3 actual, per\u00f2 qu\u00e8 passaria si pogu\u00e9ssim diagnosticar el c\u00e0ncer abans que estigu\u00e9s en una fase tan avan\u00e7ada? Seria com intentar apagar un incendi a casa quan nom\u00e9s hi ha unes poques espurnes o fer-ho amb un incendi que ha pres i s’escampa de manera imparable per diferents habitacions.<\/p>\n

Un equip d’investigadors de diversos pa\u00efsos, coordinat pel prof.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[520],"tags":[],"class_list":["post-2445","post","type-post","status-publish","format-standard","hentry","category-divulgacio-cientifica"],"acf":[],"yoast_head":"\nUn xip permetr\u00e0 detectar el c\u00e0ncer de manera preco\u00e7 - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/un-xip-permetra-detectar-el-cancer-de-manera-precoc\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un xip permetr\u00e0 detectar el c\u00e0ncer de manera preco\u00e7 - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Per Montserrat Capdevila Freixas, \u00c0rea de Ci\u00e8ncia i Medi Ambient de l’Obra Social “la Caixa”. 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