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Membres del grup de recerca del VHIR que porten a terme el projecte CEMARK que compta amb el suport de CaixaImpulse. (Font: CaixaImpulse \/ Obra Social “la Caixa”)<\/p>\n

Post d’Eva Col\u00e1s Ortega<\/strong>, investigadora del Grup de Recerca Biom\u00e8dica de Ginecologia del Vall d’Hebron Institut de Recerca (VHIR)<\/p>\n

El projecte CEMARK<\/a>, que compta amb el suport de CaixaImpulse de l’Obra Social “la Caixa” i de Caixa Capital Risc, ara \u00e9s en el seu moment m\u00e9s dol\u00e7. Va n\u00e9ixer fa cinc anys gr\u00e0cies al Dr. Antonio Gil i el seu equip cl\u00ednic del Servei de Ginecologia de l’Hospital Vall d’Hebron, que van veure una clara necessitat de millorar el proc\u00e9s diagn\u00f2stic del c\u00e0ncer d’endometri.<\/p>\n

Actualment, el diagn\u00f2stic de c\u00e0ncer d’endometri \u00e9s un proc\u00e9s tedi\u00f3s que es fa a un gran nombre de dones del nostre pa\u00eds, aproximadament a l’11% de la poblaci\u00f3 de dones postmenop\u00e0usiques.<\/p>\n

Aix\u00f2 es deu al fet que el c\u00e0ncer d’endometri presenta un s\u00edmptoma molt clar: un sagnat vaginal anormal, que alarma la pacient i el metge i que dispara el diagn\u00f2stic d’un possible c\u00e0ncer d’endometri. Tanmateix, el sagnat anormal tamb\u00e9 \u00e9s un s\u00edmptoma que passa en moltes altres malalties benignes ginecol\u00f2giques i, conseq\u00fcentment, la majoria de pacients que se sotmeten al proc\u00e9s diagn\u00f2stic no pateixen c\u00e0ncer d’endometri. Aix\u00f2 s\u00ed, cal tenir en compte que el c\u00e0ncer d’endometri no \u00e9s una malaltia infreq\u00fcent: \u00e9s el quart c\u00e0ncer m\u00e9s com\u00fa en les dones i cal diagnosticar-lo com m\u00e9s aviat millor per poder tractar-lo i curar-lo amb garanties d’\u00e8xit.<\/p>\n

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Els doctors Eva Col\u00e1s i Antonio Gil. (Font: VHIR \/ CaixaImpulse \/ Obra Social “la Caixa”)<\/p>\n

CEMARK, una prova diagn\u00f2stica no invasiva<\/strong><\/p>\n

En aquest moment, el diagn\u00f2stic est\u00e0ndard est\u00e0 basat en l’observaci\u00f3 de c\u00e8l\u00b7lules malignes en una bi\u00f2psia endometrial per\u00f2 pot donar-se el cas que no s’obtinguin prou c\u00e8l\u00b7lules perqu\u00e8 la prova sigui v\u00e0lida. Aquesta situaci\u00f3 es dona en un 22% dels diagn\u00f2stics i la resposta \u00e9s clara: aquestes pacients han de tornar al ginec\u00f2leg per sotmetre’s a una prova diagn\u00f2stica addicional, que \u00e9s invasiva i est\u00e0 associada a complicacions per a la pacient i a elevades despeses sanit\u00e0ries. Hem trobat un problema cl\u00ednic, i el nostre objectiu \u00e9s clar: fer possible el diagn\u00f2stic sense necessitat de fer bi\u00f2psies invasives.<\/p>\n

Juntament amb els doctors Antonio Gil, Silvia Cabrera i Elena Mart\u00ednez, les persones que han estat i s\u00f3n al Servei de Ginecologia \u2014des de zeladors i infermeres fins a cl\u00ednics\u2014 els pat\u00f2legs, els que treballen al Grup d’Investigaci\u00f3 Biom\u00e8dica en Ginecologia, i els treballadors del VHIR i en general del Campus Vall d’Hebron, tots som necessaris per posar en marxa l’engranatge perfecte que permet el disseny i l’execuci\u00f3 del projecte de recerca que aportar\u00e0 la soluci\u00f3 al diagn\u00f2stic: el projecte CEMARK. A dia d’avui, podem dir que el diagn\u00f2stic sense proves invasives \u00e9s factible, gr\u00e0cies al fet que ara podem fer un diagn\u00f2stic sense necessitat de tenir c\u00e8l\u00b7lules a la bi\u00f2psia endometrial. CEMARK aconsegueix diagnosticar el c\u00e0ncer d’endometri a partir del fluid endometrial, mitjan\u00e7ant un f\u00e0cil assaig basat en la detecci\u00f3 de dues prote\u00efnes.<\/p>\n

El cam\u00ed continua, ja que hem de dur CEMARK a la pr\u00e0ctica cl\u00ednica i dur a terme els passos de valoritzaci\u00f3, de desenvolupament del kit final, de les proves en m\u00e9s pacients… Cal seguir treballant, amb la mateixa motivaci\u00f3 i ganes d’innovar, amb un gran equip, per\u00f2 amb un horitz\u00f3 cada vegada m\u00e9s proper.<\/p>\n

M\u00e9s informaci\u00f3<\/strong><\/p>\n

Projecte CEMARK, amb el suport de CaixaImpulse<\/a><\/p>\n<\/p><\/div>\n

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Membres del grup de recerca del VHIR que porten a terme el projecte CEMARK que compta amb el suport de CaixaImpulse. (Font: CaixaImpulse \/ Obra Social “la Caixa”)<\/p>\n

Post d’Eva Col\u00e1s Ortega, investigadora del Grup de Recerca Biom\u00e8dica de Ginecologia del Vall d’Hebron Institut de Recerca (VHIR)<\/p>\n