La recerca posa fre a l\u2019hepatitis - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/la-recerca-posa-fre-a-lhepatitis\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La recerca posa fre a l\u2019hepatitis - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Post de l\u2019Obra Social \u201dla Caixa\u201d Hepatitis. f. Malaltia inflamat\u00f2ria que afecta el fetge. La seva causa pot ser infecciosa, immunit\u00e0ria o t\u00f2xica. El dia 28 de juliol se celebra el Dia Mundial contra l\u2019Hepatitis, malaltia que, segons l\u2019Organitzaci\u00f3 Mundial de la Salut (OMS), tan sols l\u2019any 2015 es va cobrar la vida de m\u00e9s d\u20191,3 milions de persones arreu del m\u00f3n. Les infeccions bacterianes, el consum de subst\u00e0ncies t\u00f2xiques o algunes malalties immunit\u00e0ries poden causar hepatitis; no obstant aix\u00f2, el seu origen m\u00e9s com\u00fa \u00e9s la infecci\u00f3 per virus. Dissenyat per Ibrandify \/ Freepik. 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Malaltia inflamat\u00f2ria que afecta el fetge. La seva causa pot ser infecciosa, immunit\u00e0ria o t\u00f2xica. El dia 28 de juliol se celebra el Dia Mundial contra l\u2019Hepatitis, malaltia que, segons l\u2019Organitzaci\u00f3 Mundial de la Salut (OMS), tan sols l\u2019any 2015 es va cobrar la vida de m\u00e9s d\u20191,3 milions de persones arreu del m\u00f3n. Les infeccions bacterianes, el consum de subst\u00e0ncies t\u00f2xiques o algunes malalties immunit\u00e0ries poden causar hepatitis; no obstant aix\u00f2, el seu origen m\u00e9s com\u00fa \u00e9s la infecci\u00f3 per virus. Dissenyat per Ibrandify \/ Freepik. 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Post de l\u2019Obra Social \u201dla Caixa\u201d<\/strong><\/p>\n

Hepatitis<\/strong>. f. Malaltia inflamat\u00f2ria que afecta el fetge. La seva causa pot ser infecciosa, immunit\u00e0ria o t\u00f2xica.<\/span><\/p>\n

El dia 28 de juliol se celebra el Dia Mundial contra l\u2019Hepatitis, malaltia que, segons l\u2019Organitzaci\u00f3 Mundial de la Salut (OMS), tan sols l\u2019any 2015 es va cobrar la vida de m\u00e9s d\u20191,3 milions de persones arreu del m\u00f3n. Les infeccions bacterianes, el consum de subst\u00e0ncies t\u00f2xiques o algunes malalties immunit\u00e0ries poden causar hepatitis; no obstant aix\u00f2, el seu origen m\u00e9s com\u00fa \u00e9s la infecci\u00f3 per virus.<\/p>\n

$\"\"$
Dissenyat per Ibrandify \/ Freepik.<\/span><\/p>\n

Els virus de l\u2019hepatitis m\u00e9s estudiats s\u00f3n els denominats virus A, B, C, D i E, i el B i el C s\u00f3n els responsables de la versi\u00f3 m\u00e9s greu de la malaltia. Els virus A i E es transmeten per ingesti\u00f3 d\u2019aigua o aliments contaminats. En canvi, el contagi de les hepatitis B, C i D t\u00e9 lloc per contacte amb sang de persones infectades. En el cas del virus de l\u2019hepatitis B, tamb\u00e9 es pot transmetre a trav\u00e9s de fluids corporals, com el semen o la saliva.<\/p>\n

Hepatitis i sida<\/strong><\/p>\n

Les hepatitis B i C constitueixen un important problema de salut global, amb prop de 500 milions de persones infectades arreu del m\u00f3n. La inflamaci\u00f3 produ\u00efda per ambd\u00f3s virus pot cronificar i evolucionar cap a una fibrosi hep\u00e0tica, una cirrosi i fins i tot un c\u00e0ncer de fetge.<\/p>\n

Cal destacar que els virus B i C comparteixen algunes de les vies de transmissi\u00f3 del virus de la immunodefici\u00e8ncia humana (VIH), causant del sida, de manera que la coinfecci\u00f3 \u00e9s molt freq\u00fcent en aquests pacients. Des d\u2019IrsiCaixa<\/a>, el grup de recerca dirigit per Miguel \u00c1ngel Mart\u00ednez<\/a> cerca nous biomarcadors que permetin predir quins pacients progressaran m\u00e9s de pressa en la seva malaltia hep\u00e0tica. \u201cFins fa pocs anys, prop del 40 % dels pacients de la Unitat de VIH de l\u2019Hospital Germans Trias i Pujol, on s\u2019ubica l\u2019IrsiCaixa, estaven coinfectats amb el virus de l\u2019hepatitis C (VHC)\u201d, explica Mart\u00ednez. \u201cAvui, gr\u00e0cies als nous tractaments antivirals d\u2019acci\u00f3 directa, m\u00e9s del 95 % dels pacients amb VIH estan curats d\u2019hepatitis C\u201d.<\/p>\n

$\"\"$
Investigadors del grup de Variabilitat Gen\u00e8tica i Fenot\u00edpica del VIH i el VHC de l\u2019IrsiCaixa.<\/span><\/p>\n

En els casos de coinfecci\u00f3, el VIH provoca que el dany hep\u00e0tic causat pel VHC s\u2019acceleri. \u201cPer predir com progressar\u00e0 el dany hep\u00e0tic, estudiem els microARNs circulants en sang perif\u00e8rica. Aquestes mol\u00e8cules tamb\u00e9 es fan servir com a biomarcadors en altres patologies com el c\u00e0ncer i la malaltia d\u2019Alzheimer\u201d, apunta Mart\u00ednez.<\/p>\n

Acc\u00e9s al tractament<\/strong><\/p>\n

A la nostra societat, gr\u00e0cies als aven\u00e7os de la pr\u00e0ctica m\u00e8dica i a la reducci\u00f3 de l\u2019\u00fas de drogues injectades, els nous casos d\u2019hepatitis B i C han disminu\u00eft. No obstant aix\u00f2, l\u2019erradicaci\u00f3 de l\u2019hepatitis continua sent dif\u00edcil a causa de l\u2019elevada taxa de reinfecci\u00f3 d\u2019antics pacients. A m\u00e9s, encara que existeixen vacunes eficaces per prevenir les infeccions pels virus A, B i E, en els pa\u00efsos en desenvolupament s\u00f3n poques les persones infectades que tenen un diagn\u00f2stic adequat, i menys encara les que aconsegueixen rebre tractament. Per aix\u00f2, l\u2019OMS ha desenvolupat una estrat\u00e8gia mundial contra les hepatitis v\u00edriques<\/a> amb la finalitat d\u2019oferir cobertura sanit\u00e0ria a totes les persones que les pateixin i aturar-ne la transmissi\u00f3.<\/p>\n

\u00a0<\/p>\n

Refer\u00e8ncies:<\/span>
\u2022 <\/span>Campanya OMS: Dia Mundial de l\u2019Hepatitis 2017<\/a>.<\/span>
\u2022 <\/span>Estrat\u00e8gia mundial del sector de la salut contra les hepatitis v\u00edriques, 2016-2021<\/a>.<\/span>
\u2022 <\/span>Franco S, et al. Large-scale screening of circulating microRNAs in individuals with HIV-1 mono-infections reveals specific liver damage signatures<\/a>. Antiviral Res. 2018 Jul; 155:106-114. doi: 10.1016\/j.antiviral.2018.05.008. Epub 2018 May 25.<\/span><\/p>\n<\/p><\/div>\n

<\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<\/p>\n

Post de l\u2019Obra Social \u201dla Caixa\u201d<\/p>\n

Hepatitis. f. Malaltia inflamat\u00f2ria que afecta el fetge. La seva causa pot ser infecciosa, immunit\u00e0ria o t\u00f2xica.<\/p>\n

$\"\"$
Dissenyat per Ibrandify \/ Freepik.<\/p>\n