<\/iframe> Cr\u00e8dits: La seq\u00fc\u00e8ncia sobre el cicle de vida del Plasmodium<\/em> \u00e9s cortesia de Drew Berry, del <a href=\"https:\/\/www.wehi.edu.au\/wehi-tv\/malaria-lifecycle-part-1-human-host\" rel=\"noopener noreferrer\" target=\"_blank\">Walter and Elisa Hall Institute of Medical Research<\/a>. M\u00fasica cedida per <a href=\"http:\/\/www.bensound.com\/\" rel=\"noopener noreferrer\" target=\"_blank\">bensound.com<\/a><\/span><\/p>\n El 1955 es va posar en marxa el primer programa mundial destinat a erradicar la mal\u00e0ria. M\u00e9s de seixanta anys despr\u00e9s, gaireb\u00e9 un centenar de pa\u00efsos i prop de la meitat de la poblaci\u00f3 mundial continuen exposats a aquesta malaltia parasit\u00e0ria potencialment mortal. La realitat \u00e9s que, el 2017, es van produir 219 milions de casos i m\u00e9s de 400.000 morts de mal\u00e0ria, i l\u2019\u00c0frica va ser el continent m\u00e9s castigat.<\/p>\n Amb motiu del Dia Mundial de la Mal\u00e0ria, volem destacar dos projectes impulsats per \u201dla Caixa\u201d que persegueixen, mitjan\u00e7ant estrat\u00e8gies ben diferents, contribuir a la fita establerta l\u2019any 1955: eliminar, definitivament, la mal\u00e0ria a escala global.<\/p>\n El fetge: el tal\u00f3 d\u2019Aquil\u00b7les de la mal\u00e0ria?<\/strong><\/p>\n Quan aprofundim en qu\u00e8 causa la mal\u00e0ria, topem amb un protozou del g\u00e8nere Plasmodium<\/em> que es transmet a trav\u00e9s de la picada d\u2019algunes esp\u00e8cies del mosquit Anopheles<\/em>. Una vegada el par\u00e0sit envaeix un mam\u00edfer, aquest viatja pel torrent sanguini fins a les c\u00e8l\u00b7lules hep\u00e0tiques, on es reprodueix de manera massiva. En menys de dos dies, aquestes c\u00e8l\u00b7lules es trenquen i alliberen m\u00faltiples pat\u00f2gens a la sang. <a href=\"https:\/\/imm.medicina.ulisboa.pt\/en\/investigacao\/labs\/mota-lab\/\" rel=\"noopener noreferrer\" target=\"_blank\">Maria M. Mota<\/a>, directora executiva de l\u2019Institut de Medicina Molecular (<a href=\"https:\/\/imm.medicina.ulisboa.pt\/en\/\" rel=\"noopener noreferrer\" target=\"_blank\">iMM<\/a>) de Lisboa (Portugal), lidera una recerca que se centra, justament, en el paper que t\u00e9 el fetge en el cicle vital del Plasmodium<\/em>. El projecte, seleccionat a la Primera\u00a0<a href=\"https:\/\/obrasociallacaixa.org\/es\/investigacion-y-becas\/convocatorias-de-investigacion\/convocatoria-de-investigacion-en-salud\/descripcion-del-programa\" rel=\"noopener noreferrer\" target=\"_blank\">Convocat\u00f2ria de Recerca en Salut de \u201dla Caixa\u201d<\/a>, t\u00e9 com a objectiu obrir nous tractaments que permetin alterar la reproducci\u00f3 del par\u00e0sit a les c\u00e8l\u00b7lules hep\u00e0tiques fins que aconsegueixin frenar-la.<\/p>\n <img decoding=\"async\" alt=\"\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2020\/04\/ca\/Liver_Malaria.jpg\" style=\"width: 400px; height: 400px;\"\/> Hepat\u00f2cits infectats pel par\u00e0sit de la mal\u00e0ria (en fluoresc\u00e8ncia blava). Imatge cedida per l\u2019Institut de Medicina Molecular (<a href=\"https:\/\/imm.medicina.ulisboa.pt\/en\/\" rel=\"noopener noreferrer\" target=\"_blank\">iMM<\/a>) de Lisboa (Portugal).<\/span><\/p>\n El projecte BOHEMIA: matar el mosquit quan pica<\/strong><\/p>\n Les xarxes mosquiteres impregnades d\u2019insecticida han estat i continuen sent una de les armes principals per lluitar contra la mal\u00e0ria. L\u2019\u00e8xit d\u2019aquesta mesura ha consistit, doncs, a atacar el vehicle que promou la propagaci\u00f3 del par\u00e0sit i no a destruir el par\u00e0sit en si. No obstant aix\u00f2, la creixent resist\u00e8ncia dels mosquits davant els insecticides exigeix desenvolupar nous enfocaments que dificultin la transmissi\u00f3 d\u2019aquesta malaltia.<\/p>\n L\u2019Institut de Salut Global de Barcelona (<a href=\"http:\/\/www.isglobal.org\/\" rel=\"noopener noreferrer\" target=\"_blank\">ISGlobal<\/a>), impulsat per \u201dla Caixa\u201d, lidera un consorci que implementa una nova estrat\u00e8gia per prevenir la mal\u00e0ria. Per a aix\u00f2, fa servir una f\u00f3rmula innovadora que es basa en l\u2019\u00fas de la ivermectina, un f\u00e0rmac que, administrat a persones i a bestiar, aconsegueix matar el mosquit infectat just en el moment en qu\u00e8 es produeix la picada. El <a href=\"https:\/\/www.isglobal.org\/-\/bohemia\" rel=\"noopener noreferrer\" target=\"_blank\">projecte BOHEMIA<\/a>, impulsat i finan\u00e7at per\u00a0<a data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/unitaid.org&source=gmail&ust=1567858781509000&usg=AFQjCNHy_71_Ut2JLoV3Y6s4yPrwsG2c_w\" href=\"http:\/\/unitaid.org\/\" rel=\"noopener noreferrer\" target=\"_blank\">Unitaid<\/a>, avaluar\u00e0 l\u2019impacte d\u2019aquesta mesura en dos dels pa\u00efsos africans en els quals la mal\u00e0ria \u00e9s m\u00e9s prevalent: Tanz\u00e0nia i Mo\u00e7ambic.<\/p>\n Per\u00f2 els esfor\u00e7os a Mo\u00e7ambic no es redueixen a BOHEMIA. De manera paral\u00b7lela, ISGlobal ha impulsat l\u2019Alian\u00e7a Mo\u00e7ambicana per a l\u2019Eliminaci\u00f3 de la Mal\u00e0ria (<a href=\"https:\/\/www.isglobal.org\/-\/mozambican-alliance-towards-elimination-of-malaria-maltem-\" rel=\"noopener noreferrer\" target=\"_blank\">MALTEM<\/a>), un programa de 5 anys que tamb\u00e9 t\u00e9 el suport de \u201dla Caixa\u201d. Des dels inicis, el 2014, MALTEM es va centrar a implementar un paquet de mesures destinat a reduir de manera significativa el nombre d\u2019afectats per Plasmodium<\/em> en aquest pa\u00eds. Despr\u00e9s dels dos primers anys d\u2019intervencions al districte de Magude (prov\u00edncia de Mapute), la prevalen\u00e7a de la infecci\u00f3 es va aconseguir disminuir en un 71 %. Una gran fita per a una poblaci\u00f3 que viu en un dels deu pa\u00efsos amb m\u00e9s c\u00e0rrega de mal\u00e0ria del m\u00f3n.<\/p>\n<\/p><\/div>\n<\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<\/p>\n <iframe loading=\"lazy\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\" frameborder=\"0\" height=\"225\" src=\"https:\/\/www.youtube.com\/embed\/p6zCU1tShds\" width=\"400\"><\/iframe> Cr\u00e8dits: La seq\u00fc\u00e8ncia sobre el cicle de vida del Plasmodium<\/em> \u00e9s cortesia de Drew Berry, del <a href=\"https:\/\/www.wehi.edu.au\/wehi-tv\/malaria-lifecycle-part-1-human-host\" rel=\"noopener noreferrer\" target=\"_blank\">Walter and Elisa Hall Institute of Medical Research<\/a>. M\u00fasica cedida per <a href=\"http:\/\/www.bensound.com\/\" rel=\"noopener noreferrer\" target=\"_blank\">bensound.com<\/a><\/p>\n El 1955 es va posar en marxa el primer programa mundial destinat a erradicar la mal\u00e0ria. M\u00e9s de seixanta anys despr\u00e9s, gaireb\u00e9 un centenar de pa\u00efsos i prop de la meitat de la poblaci\u00f3 mundial continuen exposats a aquesta malaltia parasit\u00e0ria potencialment mortal. La realitat \u00e9s que, el 2017, es van produir 219 milions de casos i m\u00e9s de 400.000 morts de mal\u00e0ria, i l\u2019\u00c0frica va ser el continent m\u00e9s castigat.<\/p>\n Amb motiu del Dia Mundial de la Mal\u00e0ria,<\/p>\n","protected":false},"author":1,"featured_media":2704,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[519],"tags":[365],"class_list":["post-2025","post","type-post","status-publish","format-standard","hentry","category-investigacio","tag-recerca"],"acf":[],"yoast_head":"\n<title>Dues estrat\u00e8gies per v\u00e8ncer la mal\u00e0ria - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dues estrat\u00e8gies per v\u00e8ncer la mal\u00e0ria - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Cr\u00e8dits: La seq\u00fc\u00e8ncia sobre el cicle de vida del Plasmodium \u00e9s cortesia de Drew Berry, del Walter and Elisa Hall Institute of Medical Research. M\u00fasica cedida per bensound.com El 1955 es va posar en marxa el primer programa mundial destinat a erradicar la mal\u00e0ria. M\u00e9s de seixanta anys despr\u00e9s, gaireb\u00e9 un centenar de pa\u00efsos i prop de la meitat de la poblaci\u00f3 mundial continuen exposats a aquesta malaltia parasit\u00e0ria potencialment mortal. La realitat \u00e9s que, el 2017, es van produir 219 milions de casos i m\u00e9s de 400.000 morts de mal\u00e0ria, i l\u2019\u00c0frica va ser el continent m\u00e9s castigat. Amb motiu del Dia Mundial de la Mal\u00e0ria,\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/\" \/>\n<meta property=\"og:site_name\" content=\"Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"article:published_time\" content=\"2019-04-24T00:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-05-05T08:31:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2020\/04\/ca\/Liver_Malaria.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"400\" \/>\n\t<meta property=\"og:image:height\" content=\"400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"La Caixa\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrit per\" \/>\n\t<meta name=\"twitter:data1\" content=\"La Caixa\" \/>\n\t<meta name=\"twitter:label2\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minuts\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/\",\"url\":\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/\",\"name\":\"Dues estrat\u00e8gies per v\u00e8ncer la mal\u00e0ria - Blog CaixaCi\u00e8ncia\",\"isPartOf\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2020\/04\/ca\/Liver_Malaria.jpg\",\"datePublished\":\"2019-04-24T00:00:00+00:00\",\"dateModified\":\"2020-05-05T08:31:12+00:00\",\"author\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/#\/schema\/person\/c4ed33a98e6581c876664e7035da245a\"},\"inLanguage\":\"ca\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/#primaryimage\",\"url\":\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2020\/04\/ca\/Liver_Malaria.jpg\",\"contentUrl\":\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2020\/04\/ca\/Liver_Malaria.jpg\",\"width\":400,\"height\":400},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/blog.caixaresearch.org\/#website\",\"url\":\"https:\/\/blog.caixaresearch.org\/\",\"name\":\"Blog CaixaCi\u00e8ncia\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/blog.caixaresearch.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ca\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/blog.caixaresearch.org\/#\/schema\/person\/c4ed33a98e6581c876664e7035da245a\",\"name\":\"La Caixa\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\/\/blog.caixaresearch.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/d49b93050814699a8c78e1e6223735d5?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/d49b93050814699a8c78e1e6223735d5?s=96&d=mm&r=g\",\"caption\":\"La Caixa\"},\"sameAs\":[\"https:\/\/blog.caixaresearch.org\"],\"url\":\"https:\/\/blog.caixaresearch.org\/ca\/author\/caixaciencialamagnetica-net\/\"}]}<\/script>\n","yoast_head_json":{"title":"Dues estrat\u00e8gies per v\u00e8ncer la mal\u00e0ria - Blog CaixaCi\u00e8ncia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/blog.caixaresearch.org\/ca\/dues-estrategies-per-vencer-la-malaria\/","og_locale":"ca_ES","og_type":"article","og_title":"Dues estrat\u00e8gies per v\u00e8ncer la mal\u00e0ria - Blog CaixaCi\u00e8ncia","og_description":"Cr\u00e8dits: La seq\u00fc\u00e8ncia sobre el cicle de vida del Plasmodium \u00e9s cortesia de Drew Berry, del Walter and Elisa Hall Institute of Medical Research. 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