Computaci\u00f3 avan\u00e7ada al servei d\u2019una medicina efica\u00e7 i personalitzada - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/computacio-avancada-al-servei-duna-medicina-eficac-i-personalitzada\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Computaci\u00f3 avan\u00e7ada al servei d\u2019una medicina efica\u00e7 i personalitzada - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Post escrit per David Carrera i Jord\u00e0 Polo, investigadors del Barcelona Supercomputing Center – Centre Nacional de Supercomputaci\u00f3 (BSC-CNS). Jord\u00e0 Polo, investigador del BSC-CNS En l\u2019\u00e0mbit de la biomedicina, identificar alteracions gen\u00f2miques associades a malalties ha esdevingut un dels passos m\u00e9s importants a l\u2019hora de classificar i diagnosticar pacients. Tanmateix, aquestes metodologies, considerades una de les bases del futur de la medicina personalitzada, encara no estan a l\u2019abast de la majoria de la comunitat biom\u00e8dica.\u00a0 Al Barcelona Supercomputing Center (BSC), treballem per millorar les eines per identificar aquestes alteracions gen\u00f2miques, n\u2019optimitzem l\u2019efici\u00e8ncia i en redu\u00efm el cost. 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Post escrit per <\/span>David Carrera <\/strong>i Jord\u00e0 Polo<\/strong>, investigadors del Barcelona Supercomputing Center – Centre Nacional de Supercomputaci\u00f3 (BSC-CNS).<\/p>\n

$\"\"$
Jord\u00e0 Polo, investigador del BSC-CNS<\/span><\/p>\n

En l\u2019\u00e0mbit de la biomedicina, identificar alteracions gen\u00f2miques associades a malalties ha esdevingut un dels passos m\u00e9s importants a l\u2019hora de classificar i diagnosticar pacients. Tanmateix, aquestes metodologies, considerades una de les bases del futur de la medicina personalitzada, encara no estan a l\u2019abast de la majoria de la comunitat biom\u00e8dica.\u00a0<\/p>\n

Al Barcelona Supercomputing Center (<\/span>BSC<\/a>), treballem per millorar les eines per identificar aquestes alteracions gen\u00f2miques, n\u2019optimitzem l\u2019efici\u00e8ncia i en redu\u00efm el cost. Ho fem de la m\u00e0 del Massachusetts Institute of Technology (MIT<\/a>) a trav\u00e9s del programa MIT-Spain \u201dla Caixa\u201d Foundation Seed Fund<\/a>.\u00a0<\/p>\n

Actualment, les alteracions gen\u00f2miques s\u2019identifiquen a partir de l\u2019extracci\u00f3 i seq\u00fcenciaci\u00f3 de les mostres dels pacients i la seva posterior an\u00e0lisi amb models computacionals. Tot plegat \u00e9s un proc\u00e9s lent i complex.\u00a0<\/p>\n

La seq\u00fcenciaci\u00f3 de nova generaci\u00f3 ha perm\u00e8s reduir dr\u00e0sticament el cost i el temps de digitalitzaci\u00f3 del genoma hum\u00e0, per\u00f2 el preu d\u2019emmagatzemar, processar i analitzar les dades no ha evolucionat de la mateixa manera. A m\u00e9s,\u00a0 la demanda de resultats, cada cop m\u00e9s acurats, tamb\u00e9 creix.<\/p>\n

Aix\u00ed doncs, la computaci\u00f3 \u00e9s ara el principal coll d\u2019ampolla per a aquestes noves tecnologies de medicina personalitzada. Les eines actuals de processament i an\u00e0lisi per identificar alteracions requereixen una gran capacitat de c\u00e0lcul i d\u2019emmagatzemament de dades que, justament, centres com el BSC poden oferir.<\/p>\n

$\"\"$ <\/p>\n

El nostre projecte, \u201cGenomic Computation using Flash and Accelerators\u201d, es basa en un protocol inform\u00e0tic, anomenat <\/span>SMuFin<\/a>, per identificar mutacions pat\u00f2genes i dissenyat per treure el m\u00e0xim profit de noves tecnologies, com ara acceleradors i mem\u00f2ries no vol\u00e0tils.\u00a0<\/p>\n

D\u2019aquesta manera, un sol ordinador ser\u00e0 capa\u00e7 d\u2019analitzar un pacient en nom\u00e9s unes hores. M\u00e8todes com aquest, que combinen protocols dissenyats i optimitzats per a noves generacions d\u2019ordinadors, s\u00f3n l\u2019\u00fanica soluci\u00f3 realista per les an\u00e0lisis gen\u00f2miques a gran escala.<\/p>\n

Aquest projecte \u00e9s un dels dotze seleccionats a la primera convocat\u00f2ria <\/span>MIT-Spain \u201dla Caixa\u201d Foundation Seed Fund<\/a>. Aquest programa, impulsat per \u201dla Caixa\u201d<\/a> i el Massachusetts Institute of Technology<\/a> (MIT), pret\u00e9n potenciar la col\u00b7laboraci\u00f3 entre grups de recerca espanyols i del MIT, com tamb\u00e9 la transversalitat en la generaci\u00f3 de coneixement i potenciar la recerca de frontera.<\/p>\n<\/p><\/div>\n

<\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<\/p>\n

Post escrit per David Carrera i Jord\u00e0 Polo, investigadors del Barcelona Supercomputing Center – Centre Nacional de Supercomputaci\u00f3 (BSC-CNS).<\/p>\n

$\"\"$
Jord\u00e0 Polo, investigador del BSC-CNS<\/p>\n