{"id":13626,"date":"2026-05-19T10:56:00","date_gmt":"2026-05-19T09:56:00","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=13626"},"modified":"2026-05-19T10:56:00","modified_gmt":"2026-05-19T09:56:00","slug":"instantania-del-mes-patrons-secrets-de-lesser","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/instantania-del-mes-patrons-secrets-de-lesser\/","title":{"rendered":"Instant\u00e0nia del mes: \u00abPatrons secrets de l\u2019\u00c9sser\u00bb"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-13616\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/p>\n<p><span style=\"font-weight: 300;\">Qu\u00e8 tenen en com\u00fa una micrografia cel\u00b7lular i una catifa persa? A primera vista totes dues s\u00f3n geometries que capturen un teixit, un entramat de patrons crom\u00e0tics.<\/span><\/p>\n<p><span style=\"font-weight: 300;\">En aquest lliurament de la <\/span><i><span style=\"font-weight: 300;\">Instant\u00e0nia del mes<\/span><\/i><span style=\"font-weight: 300;\"> descobrirem com es connecta aquesta met\u00e0fora a trav\u00e9s de la simbologia del cinema i qu\u00e8 \u00e9s el que realment evidencia l\u2019estudi al qual pertany la imatge. I \u00e9s que rere una aparent quietud s\u2019amaga<\/span><b> una \u00abbatalla\u00bb cel\u00b7lular digna d\u2019un gui\u00f3 cinematogr\u00e0fic<\/b><span style=\"font-weight: 300;\">, amb els seus herois i malvats i un <\/span><i><span style=\"font-weight: 300;\">tempo<\/span><\/i><span style=\"font-weight: 300;\"> narratiu que ho determina tot. <\/span><b>En s\u00f3n les protagonistes les c\u00e8l\u00b7lules senescents, aut\u00e8ntiques \u00abc\u00e8l\u00b7lules zombis\u00bb que deixen de dividir-se, per\u00f2 no es moren. <\/b><span style=\"font-weight: 300;\">En un entorn tumoral, aquest fenomen \u00e9s una arma de doble tall: al principi \u00e9s bo perqu\u00e8 actua com a fre per a la divisi\u00f3 de c\u00e8l\u00b7lules danyades que<\/span> <span style=\"font-weight: 300;\">alimentarien el tumor, per\u00f2 a llarg termini les c\u00e8l\u00b7lules zombis s\u2019acumulen i alliberen subst\u00e0ncies inflamat\u00f2ries que acaben creant les condicions per ajudar el tumor a cr\u00e9ixer.<\/span> <b>Tanmateix, en la trama d\u2019aquest desenvolupament tumoral hi ha altres implicats, com revela un nou estudi.<\/b> <span style=\"font-weight: 300;\">Amb aix\u00f2 el gir de gui\u00f3 est\u00e0 servit.<\/span><\/p>\n<p><span style=\"font-weight: 300;\">Per explorar aquesta instant\u00e0nia de l\u2019estudi dut a terme al Vall d\u2019Hebron Institut d\u2019Oncologia (VHIO) i l\u2019Hospital del Mar Research Institute (HMRIB), i publicat a <\/span><a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adx2988\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 300;\">Science Advances<\/span><\/i><\/a><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 300;\">encreuem dues visions. Tenim la mirada cient\u00edfica dels investigadors de l\u2019estudi en q\u00fcesti\u00f3, membres del grup de recerca <\/span><a href=\"https:\/\/www.researchmar.net\/programesrecerca\/cancer\/redireccio_immune.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 300;\">Redirecci\u00f3 Immune<\/span><\/a><span style=\"font-weight: 300;\"> de l\u2019HMRIB: <\/span><a href=\"https:\/\/caixaresearch.org\/ca\/convocatoria-caixaresearch-investigacio-salut-2022-projecte-cancer-mama\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 300;\">Joaqu\u00edn Arribas<\/span><\/a><span style=\"font-weight: 300;\">, l\u00edder del grup, director de l\u2019institut i investigador Health Research; <\/span><a href=\"https:\/\/becarios.fundacionlacaixa.org\/ca\/pau-garcia-baucells-B005771\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 300;\">Pau Garcia Baucells<\/span><\/a><span style=\"font-weight: 300;\">, membre de la comunitat de becaris de la Fundaci\u00f3 \u201dla\u00a0Caixa\u201d i estudiant de doctorat en Immunoter\u00e0pia Oncol\u00f2gica, i <\/span><a href=\"https:\/\/www.linkedin.com\/in\/marta-lalinde-guti%C3%A9rrez-ba440b116\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 300;\">Marta Lalinde<\/span><\/a><span style=\"font-weight: 300;\">, investigadora postdoctoral amb doble afiliaci\u00f3 al Vall d&#8217;Hebron Institut d&#8217;Oncologia (VHIO) i a l&#8217;HMRIB i primera autora de l\u2019article. I d\u2019altra banda tenim tamb\u00e9 l\u2019enfocament art\u00edstic de la cineasta <\/span><a href=\"https:\/\/becarios.fundacionlacaixa.org\/ca\/andrea-nouga-feliu-B006286?nav=true\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 300;\">Andrea Nouga Feliu<\/span><\/a><span style=\"font-weight: 300;\">, que actualment cursa un m\u00e0ster en Producci\u00f3 i Realitzaci\u00f3 Cinematogr\u00e0fica a la London Film School, gr\u00e0cies a una beca de postgrau a l\u2019estranger de la Fundaci\u00f3 \u201dla Caixa\u201d.<\/span><\/p>\n<p><b><i>Comencem amb ella.<\/i><\/b><span style=\"font-weight: 300;\">\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><b><i>Andrea, a quines refer\u00e8ncies cinematogr\u00e0fiques et recorda aquesta imatge?<\/i><\/b><\/h3>\n<p><b>Andrea (A):<\/b><span style=\"font-weight: 300;\"> La intensitat crom\u00e0tica de la imatge i la seva organitzaci\u00f3 en patrons densos <\/span><b>l\u2019apropen inesperadament a certes tradicions visuals contempor\u00e0nies iranianes<\/b><span style=\"font-weight: 300;\"> en qu\u00e8 el color, la repetici\u00f3 i l\u2019abstracci\u00f3 funcionen com a vehicles de significat. La imatge remet a la pel\u00b7l\u00edcula <\/span><a href=\"https:\/\/www.imdb.com\/es\/title\/tt0116384\/?ref_=mv_close\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 300;\">Gabbeh<\/span><\/i><\/a><span style=\"font-weight: 300;\"> (1996), de Mohsen Makhmalbaf, per l\u2019\u00fas de colors saturats que emergeixen de la foscor. <\/span><\/p>\n<div id=\"attachment_13620\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13620\" class=\"wp-image-13620\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Andrea.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Andrea.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Andrea-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Andrea-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Andrea-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Andrea-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13620\" class=\"wp-caption-text\"><em>Andrea Nouga Feliu<\/em><\/p><\/div>\n<p><span style=\"font-weight: 300;\">Em recorden la manera en qu\u00e8 la pel\u00b7l\u00edcula representa <\/span><b>les emocions humanes i la traject\u00f2ria de l\u2019individu en el seu context social a trav\u00e9s de la intensitat dels colors<\/b><span style=\"font-weight: 300;\"> i els seus diferents tons. El relat sorgeix d\u2019una catifa n\u00f2mada (<\/span><i><span style=\"font-weight: 300;\">gabbeh<\/span><\/i><span style=\"font-weight: 300;\">), els colors i els motius repetitius de la qual contenen hist\u00f2ries d\u2019amor, mem\u00f2ria i desig, de manera que es converteixen en un llenguatge visual. D\u2019una manera semblant, la micrografia mostra una superf\u00edcie vibrant on <\/span><b>les c\u00e8l\u00b7lules tenyides de blaus, vermells i grocs s\u2019organitzen com un tap\u00eds microsc\u00f2pic que, tot i que no planteja una narrativa intencional, convida a ser llegit<\/b><span style=\"font-weight: 300;\">.<\/span><\/p>\n<div id=\"attachment_13596\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13596\" class=\"wp-image-13596\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-1.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-1.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-1-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-1-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-1-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-1-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13596\" class=\"wp-caption-text\"><em>Fotograma de Gabbeh (1996), dirigida per Mohsen Makhmalbaf. Coproducci\u00f3 i distribuci\u00f3 de \u00a9 MK2 Diffusion \/ Font: BAM (Brooklyn Academy of Music)<\/em><\/p><\/div>\n<div id=\"attachment_13600\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13600\" class=\"wp-image-13600\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-2.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-2.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-2-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-2-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-2-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_gabbeh-2-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13600\" class=\"wp-caption-text\"><em>Fotograma de Gabbeh (1996), dirigida per Mohsen Makhmalbaf. Coproducci\u00f3 i distribuci\u00f3 de \u00a9 MK2 Diffusion \/ Font: IMDb<\/em><\/p><\/div>\n<p><span style=\"font-weight: 300;\">Penso tamb\u00e9 en la directora iraniana Shirin Neshat i els seus treballs de cinema experimental, per exemple, <\/span><a href=\"https:\/\/mubi.com\/en\/es\/films\/logic-of-the-birds\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 300;\">Logic of the Birds<\/span><\/i><\/a><span style=\"font-weight: 300;\">, en qu\u00e8 les multituds en moviment evoquen una recerca espiritual col\u00b7lectiva i <\/span><b>l\u2019individual es dilueix en una experi\u00e8ncia comuna<\/b><span style=\"font-weight: 300;\">. La imatge suggereix una cosa semblant: una multiplicitat d\u2019unitats que, en agrupar-se, generen una forma coherent i gaireb\u00e9 din\u00e0mica. <\/span><b>Cada c\u00e8l\u00b7lula es podria entendre com un \u00abviatger\u00bb dins d\u2019un sistema m\u00e9s gran que contribueix a una totalitat que transcendeix les seves parts.<\/b><\/p>\n<div id=\"attachment_13592\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13592\" class=\"wp-image-13592\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_birds.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_birds.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_birds-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_birds-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_birds-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_birds-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13592\" class=\"wp-caption-text\"><em>Fotograma de l\u2019obra art\u00edstica Logic of the Birds (2002), de Ghasem Ebrahimian, Shirin Neshat, Shoja Azari, Sussan Deyhim \/ Font: artangel.org.uk<\/em><\/p><\/div>\n<p>&nbsp;<\/p>\n<h3><b><i>Qu\u00e8 et transmet aquesta imatge?<\/i><\/b><\/h3>\n<p><b>A:<\/b> <b>Despr\u00e9s d\u2019embriagar-me amb la vivesa dels colors em ve de gust fixar-me en el contrari<\/b><span style=\"font-weight: 300;\">, en la foscor que actua de suport i que, al mateix temps, \u00e9s l\u2019\u00fanica cosa que fa possible l\u2019exist\u00e8ncia d\u2019aquests colors. Si calgu\u00e9s posar-hi un t\u00edtol, l\u2019anomenaria <\/span><b><i>Patrons secrets de l\u2019\u00c9sser<\/i><\/b><span style=\"font-weight: 300;\">.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><b><i>Joaqu\u00edn, des d\u2019un punt de vista cient\u00edfic, qu\u00e8 podem desxifrar en aquesta imatge?<\/i><\/b><\/h3>\n<p><b>Joaqu\u00edn (J)<\/b><span style=\"font-weight: 400;\">:<\/span><span style=\"font-weight: 300;\"> Es tracta d\u2019una <\/span><a href=\"https:\/\/www.cancer.gov\/espanol\/publicaciones\/diccionarios\/diccionario-cancer\/def\/inmunofluorescencia\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 300;\">immunofluoresc\u00e8ncia<\/span><\/a><span style=\"font-weight: 300;\"> que <\/span><b>mostra les c\u00e8l\u00b7lules senescents o c\u00e8l\u00b7lules zombi en un dels tumors<\/b><span style=\"font-weight: 300;\"> de ratol\u00ed en estadi preco\u00e7.\u00a0<\/span><\/p>\n<div id=\"attachment_13604\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13604\" class=\"wp-image-13604\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Joaquin.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Joaquin.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Joaquin-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Joaquin-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Joaquin-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Joaquin-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13604\" class=\"wp-caption-text\"><em>Joaqu\u00edn Arribas<\/em><\/p><\/div>\n<p>&nbsp;<\/p>\n<h3><b><i>I qu\u00e8 t\u00e9 d\u2019important el paper d\u2019aquestes c\u00e8l\u00b7lules en l\u2019entorn tumoral?<\/i><\/b><\/h3>\n<p><b>J<\/b><span style=\"font-weight: 400;\">:<\/span><span style=\"font-weight: 300;\"> Hem descobert que les <\/span><b>c\u00e8l\u00b7lules senescents tenen un paper determinant en la progressi\u00f3 tumoral<\/b><span style=\"font-weight: 300;\">. Aquestes c\u00e8l\u00b7lules <\/span><b>influeixen en la pres\u00e8ncia i el comportament de certs macr\u00f2fags<\/b><span style=\"font-weight: 300;\"> (c\u00e8l\u00b7lules del sistema immunitari que eliminen pat\u00f2gens i c\u00e8l\u00b7lules deteriorades) a trav\u00e9s d\u2019una <\/span><b>mol\u00e8cula anomenada CCL2<\/b><span style=\"font-weight: 300;\"> (una citocina produ\u00efda pels mateixos macr\u00f2fags, que \u00abrecluta\u00bb m\u00e9s macr\u00f2fags), cosa que alhora pot modificar l\u2019evoluci\u00f3 del tumor.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><b><i>Marta, qu\u00e8 m\u00e9s heu descobert? Com influeixen exactament aquestes c\u00e8l\u00b7lules senescents en l\u2019evoluci\u00f3 del tumor?<\/i><\/b><b><br \/>\n<\/b><\/h3>\n<p><b>Marta<\/b><span style=\"font-weight: 400;\">:<\/span><span style=\"font-weight: 300;\"> Encara no era del tot clar si les c\u00e8l\u00b7lules senescents ajuden a frenar el c\u00e0ncer o, per contra, n\u2019afavoreixen el creixement i, per tant, si \u00e9s recomanable o no eliminar-les (mitjan\u00e7ant, per exemple, f\u00e0rmacs senol\u00edtics).<\/span><\/p>\n<p><span style=\"font-weight: 300;\">Per respondre a aquesta pregunta <\/span><b>vam desenvolupar un model de ratol\u00ed transg\u00e8nic que permet eliminar aquestes c\u00e8l\u00b7lules en diferents moments de la malaltia i vam veure que el moment \u00e9s clau. Si s\u2019eliminen massa aviat, el tumor es pot tornar m\u00e9s agressiu<\/b><span style=\"font-weight: 300;\">. Tanmateix, combinant l\u2019eliminaci\u00f3 d\u2019aquestes c\u00e8l\u00b7lules <\/span><b>amb el bloqueig de la mol\u00e8cula CCL2, es pot evitar aquest efecte negatiu<\/b><span style=\"font-weight: 300;\">.<\/span><\/p>\n<p><span style=\"font-weight: 300;\">\u00c9s a dir, no es tracta nom\u00e9s de si eliminar les c\u00e8l\u00b7lules senescents frena o accelera el c\u00e0ncer, sin\u00f3 de com i quan s\u2019han d\u2019eliminar. <\/span><b>En etapes primerenques, eliminar les c\u00e8l\u00b7lules senescents sense bloquejar la CCL2 dona lloc a una atracci\u00f3 exacerbada de macr\u00f2fags<\/b><span style=\"font-weight: 300;\">, que a la vegada alliberen m\u00e9s CCL2 i creen un cercle vici\u00f3s d\u2019inflamaci\u00f3. Aquest proc\u00e9s <\/span><b>no permet la intervenci\u00f3 dels limf\u00f2cits T<\/b><span style=\"font-weight: 300;\">, que haurien d\u2019atacar el tumor, i per tant facilita que creixi lliurement i amb m\u00e9s for\u00e7a.<\/span><\/p>\n<div id=\"attachment_13608\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13608\" class=\"wp-image-13608\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Marta.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Marta.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Marta-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Marta-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Marta-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Marta-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13608\" class=\"wp-caption-text\"><em>Marta Lalinde<\/em><\/p><\/div>\n<p>&nbsp;<\/p>\n<h3><b><i>Pau, quin impacte creus que tindr\u00e0 aquest descobriment en la societat?<\/i><\/b><\/h3>\n<p><b>Pau<\/b><span style=\"font-weight: 400;\">:<\/span><span style=\"font-weight: 300;\"> Crec que el seu impacte principal \u00e9s millorar la nostra comprensi\u00f3 sobre com funciona un tumor a escala cel\u00b7lular. Entendre millor la relaci\u00f3 entre c\u00e8l\u00b7lules senescents, inflamaci\u00f3 i sistema immune \u00e9s important perqu\u00e8 <\/span><b>ens ajuda a explicar per qu\u00e8 els tumors evolucionen de formes diferents i obre la porta a estrat\u00e8gies terap\u00e8utiques m\u00e9s precises en el futur<\/b><span style=\"font-weight: 300;\">. \u00c9s un aven\u00e7 en coneixement b\u00e0sic, per\u00f2 amb una clara projecci\u00f3 biom\u00e8dica.<\/span><\/p>\n<div id=\"attachment_13612\" style=\"width: 410px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-13612\" class=\"wp-image-13612\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Pau.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Pau.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Pau-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Pau-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Pau-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Pau-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-13612\" class=\"wp-caption-text\"><em>Pau Garcia Baucells<\/em><\/p><\/div>\n<p>&nbsp;<\/p>\n<h3><b><i>Per acabar abordem una \u00faltima reflexi\u00f3. Andrea, quina relaci\u00f3 creus que hi ha entre la ci\u00e8ncia i l\u2019art?<\/i><\/b><\/h3>\n<p><span style=\"font-weight: 300;\"><strong>A:<\/strong> Tots dos neixen de dues qualitats humanes: la imaginaci\u00f3 i la creativitat. La connexi\u00f3 entre ci\u00e8ncia i art no \u00e9s tan sols est\u00e8tica, sin\u00f3 que tamb\u00e9 apunta a una relaci\u00f3 m\u00e9s profunda, ja que <\/span><b>els humans som criatures sensorials que perceben el m\u00f3n abans de comprendre\u2019l<\/b><span style=\"font-weight: 300;\">.<\/span><\/p>\n<p><span style=\"font-weight: 300;\">La <\/span><b>ci\u00e8ncia parteix de la mateixa base sensorial que l\u2019art<\/b><span style=\"font-weight: 300;\"> per identificar, traduir i interpretar all\u00f2 que percep, i construir aix\u00ed <\/span><b>models que fan intel\u00b7ligible el que \u00e9s real<\/b><span style=\"font-weight: 300;\">. En aquest sentit, la micrografia no \u00e9s nom\u00e9s un registre t\u00e8cnic, sin\u00f3 que tamb\u00e9 \u00e9s el resultat d\u2019una mirada que selecciona, il\u00b7lumina i enquadra, \u00e9s a dir, que ja cont\u00e9 una dimensi\u00f3 creativa.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><b><i>L\u2019enquadrament d\u2019una \u00abbatalla\u00bb cel\u00b7lular<\/i><\/b><\/h3>\n<p><span style=\"font-weight: 300;\">M\u00e9s enll\u00e0 de la pot\u00e8ncia visual d\u2019aquesta micrografia, <\/span><b>el que aquest estudi posa sobre la taula \u00e9s una q\u00fcesti\u00f3 d\u2019estrat\u00e8gia i precisi\u00f3<\/b><span style=\"font-weight: 300;\">. El descobriment del grup demostra que, en la lluita contra el c\u00e0ncer, no sempre n\u2019hi ha prou amb atacar l\u2019enemic; \u00e9s vital entendre com i quan cal fer-ho.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-13616\" src=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg\" alt=\"\" width=\"400\" height=\"225\" srcset=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg 1920w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-300x169.jpg 300w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-1024x576.jpg 1024w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-768x432.jpg 768w, https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/p>\n<p>Qu\u00e8 tenen en com\u00fa una micrografia cel\u00b7lular i una catifa persa? A primera vista totes dues s\u00f3n geometries que capturen un teixit, un entramat de patrons crom\u00e0tics.<\/p>\n<p>En aquest lliurament de la <i>Instant\u00e0nia del mes<\/i> descobrirem com es connecta aquesta met\u00e0fora a trav\u00e9s de la simbologia del cinema i qu\u00e8 \u00e9s el que realment evidencia l\u2019estudi al qual pertany la imatge. I \u00e9s que rere una aparent quietud s\u2019amaga una \u00abbatalla\u00bb cel\u00b7lular digna d\u2019un gui\u00f3 cinematogr\u00e0fic, amb els seus herois i malvats i un <i>tempo<\/i> narratiu que ho determina tot. En s\u00f3n les protagonistes les c\u00e8l\u00b7lules senescents, aut\u00e8ntiques \u00abc\u00e8l\u00b7lules zombis\u00bb que deixen de dividir-se, per\u00f2 no es moren.<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[520,519],"tags":[],"class_list":["post-13626","post","type-post","status-publish","format-standard","hentry","category-divulgacio-cientifica","category-investigacio"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Instant\u00e0nia del mes: \u00abPatrons secrets de l\u2019\u00c9sser\u00bb - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instant\u00e0nia del mes: \u00abPatrons secrets de l\u2019\u00c9sser\u00bb - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Qu\u00e8 tenen en com\u00fa una micrografia cel\u00b7lular i una catifa persa? A primera vista totes dues s\u00f3n geometries que capturen un teixit, un entramat de patrons crom\u00e0tics. En aquest lliurament de la Instant\u00e0nia del mes descobrirem com es connecta aquesta met\u00e0fora a trav\u00e9s de la simbologia del cinema i qu\u00e8 \u00e9s el que realment evidencia l\u2019estudi al qual pertany la imatge. I \u00e9s que rere una aparent quietud s\u2019amaga una \u00abbatalla\u00bb cel\u00b7lular digna d\u2019un gui\u00f3 cinematogr\u00e0fic, amb els seus herois i malvats i un tempo narratiu que ho determina tot. En s\u00f3n les protagonistes les c\u00e8l\u00b7lules senescents, aut\u00e8ntiques \u00abc\u00e8l\u00b7lules zombis\u00bb que deixen de dividir-se, per\u00f2 no es moren.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717\" \/>\n<meta property=\"og:site_name\" content=\"Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-19T09:56:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ubikmedia\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrit per\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ubikmedia\" \/>\n\t<meta name=\"twitter:label2\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 minuts\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717\",\"url\":\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717\",\"name\":\"Instant\u00e0nia del mes: \u00abPatrons secrets de l\u2019\u00c9sser\u00bb - Blog CaixaCi\u00e8ncia\",\"isPartOf\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717#primaryimage\"},\"image\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717#primaryimage\"},\"thumbnailUrl\":\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg\",\"datePublished\":\"2026-05-19T09:56:00+00:00\",\"author\":{\"@id\":\"https:\/\/blog.caixaresearch.org\/#\/schema\/person\/2b9d5310c27055b4862191402c387fca\"},\"inLanguage\":\"ca\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717#primaryimage\",\"url\":\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg\",\"contentUrl\":\"https:\/\/blog.caixaresearch.org\/wp-content\/uploads\/2026\/05\/Instantania-Mayo-Blog-CR-_Principal.jpg\"},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/blog.caixaresearch.org\/#website\",\"url\":\"https:\/\/blog.caixaresearch.org\/\",\"name\":\"Blog CaixaCi\u00e8ncia\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/blog.caixaresearch.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ca\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/blog.caixaresearch.org\/#\/schema\/person\/2b9d5310c27055b4862191402c387fca\",\"name\":\"Ubikmedia\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\/\/blog.caixaresearch.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ccc66bc497f8ba496f9d06e5a58a91de?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ccc66bc497f8ba496f9d06e5a58a91de?s=96&d=mm&r=g\",\"caption\":\"Ubikmedia\"},\"url\":\"https:\/\/blog.caixaresearch.org\/ca\/author\/ubikmedia\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Instant\u00e0nia del mes: \u00abPatrons secrets de l\u2019\u00c9sser\u00bb - Blog CaixaCi\u00e8ncia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/blog.caixaresearch.org\/pt-pt\/?p=13717","og_locale":"ca_ES","og_type":"article","og_title":"Instant\u00e0nia del mes: \u00abPatrons secrets de l\u2019\u00c9sser\u00bb - Blog CaixaCi\u00e8ncia","og_description":"Qu\u00e8 tenen en com\u00fa una micrografia cel\u00b7lular i una catifa persa? 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