{"id":10677,"date":"2025-07-24T16:22:44","date_gmt":"2025-07-24T15:22:44","guid":{"rendered":"https:\/\/blog.caixaresearch.org\/?p=10677"},"modified":"2025-07-24T16:22:44","modified_gmt":"2025-07-24T15:22:44","slug":"instantania-caixaresearch-desplacament","status":"publish","type":"post","link":"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-desplacament\/","title":{"rendered":"\u201cDespla\u00e7ament\u201d"},"content":{"rendered":"

\"\"<\/p>\n

Crear, observar, pensar, corregir, replantejar\u2026<\/b> Diries que aquests passos formen part del treball d\u2019un artista o d\u2019una recerca cient\u00edfica?<\/span><\/p>\n

Sense context \u00e9s dif\u00edcil triar, oi? Per\u00f2 si a l\u2019escena hi afegim pinzells i est\u00e0tues o, en canvi, pipetes o microscopis, la resposta potser sembla m\u00e9s evident. Aleshores, <\/span>podr\u00edem dir que, en ess\u00e8ncia, art i ci\u00e8ncia s\u2019assemblen m\u00e9s del que pensem?<\/b><\/p>\n

\"\"<\/p>\n

En aquesta nova Instant\u00e0nia CaixaResearch ens hi acompanyen <\/span>David Sancho<\/b><\/a>, investigador de la nostra xarxa al Centro Nacional de Investigaciones Cardiovasculares (CNIC), i <\/span>Guillermo Mora<\/b><\/a>, artista visual i becari de la Fundaci\u00f3 \u201dla Caixa\u201d.<\/span><\/p>\n

Junts partirem d\u2019una imatge cient\u00edfica per explorar un descobriment biom\u00e8dic innovador i, alhora, desvelar aquest espai compartit entre la creaci\u00f3 art\u00edstica i la recerca cient\u00edfica. <\/span>Comencem amb el Guillermo.<\/b><\/p>\n

Imagina\u2019t que aquesta imatge estigu\u00e9s exposada en una galeria d\u2019art. Qu\u00e8 hi veus?<\/b><\/p>\n

G: T\u00e9 un aspecte cartogr\u00e0fic. Hi veig moviment, alguna cosa que se separa i es despla\u00e7a. Si li hagu\u00e9s de posar un nom, seria <\/span>Despla\u00e7ament<\/i><\/b>.<\/span><\/p>\n

Si fos l\u2019obra d\u2019un artista, de qui podria ser?<\/b><\/p>\n

G: Em recorda algunes obres de l\u2019artista brit\u00e0nica <\/span>Karla Black<\/b><\/a>. Les seves instal\u00b7lacions, fetes a base de productes cosm\u00e8tics com el talc i el maquillatge en pols, es presenten com paisatges abstractes i ens conviden a redescobrir l\u2019espai.<\/span><\/p>\n

\"\"<\/p>\n

Guillermo Mora, artista visual i becari de la Fundaci\u00f3 \u201dla Caixa\u201d.<\/em><\/p>\n

Ja ho veus, David: com comenta el Guillermo, la vostra imatge podria encaixar perfectament com una pe\u00e7a d\u2019exposici\u00f3. Per\u00f2, qu\u00e8 hi veiem realment?<\/b><\/p>\n

D: Hi veiem la tinci\u00f3 d\u2019art\u00e8ries a la base de l\u2019aorta. Les zones vermelloses marquen les plaques de greix t\u00edpiques de l\u2019aterosclerosi que s\u2019acumulen a <\/span>les parets arterials<\/span>. Si aquestes plaques es trenquen, es forma un trombe que pot taponar els vasos sanguinis i provocar infarts o ictus.<\/span><\/p>\n

Ens podries explicar quin descobriment s\u2019amaga darrere la imatge?<\/b><\/p>\n

D: Hem descobert que unes c\u00e8l\u00b7lules del sistema immunol\u00f2gic anomenades<\/span> c\u00e8l\u00b7lules dendr\u00edtiques de tipo 1 <\/span><\/i>(cDC1) poden activar unes altres c\u00e8l\u00b7lules, els limf\u00f2cits T, que contribueixen a l\u2019aterosclerosi formant plaques de greix i inflamant les art\u00e8ries.<\/span><\/p>\n

Per mitj\u00e0 d\u2019imatges com aquesta, vam veure que, en eliminar les cDC1s en models animals, les plaques de greix es redueixen molt. A partir d\u2019aqu\u00ed, vam desenvolupar una ter\u00e0pia experimental en models animals que actua directament sobre aquestes c\u00e8l\u00b7lules per frenar la malaltia.<\/span><\/p>\n

Sembla un descobriment amb gran potencial. Quin impacte creieu que tindr\u00e0 en l\u2019\u00e0mbit de la salut?<\/b><\/p>\n

D: L\u2019aterosclerosi \u00e9s una de les causes principals de mort al m\u00f3n. Avui dia, es tracta controlant factors de risc com el colesterol o la pressi\u00f3 arterial.<\/span><\/p>\n

El nostre descobriment obre la porta a una nova generaci\u00f3 de ter\u00e0pies m\u00e9s eficaces i segures que, en comptes de centrar-se \u00fanicament en el colesterol, actuen sobre l\u2019origen immunitari de la malaltia. Aix\u00f2 podria millorar la vida de milions de persones, especialment de les que no responen b\u00e9 als tractaments actuals o pateixen efectes secundaris. A m\u00e9s, estableix les bases per desenvolupar ter\u00e0pies personalitzades capaces de modular amb precisi\u00f3 el sistema immunol\u00f2gic en les malalties cardiovasculars.<\/span><\/p>\n

\"\"<\/p>\n

Investigadors del CNIC. D\u2019esquerra a dreta: Sarai Mart\u00ednez, Marcos Femen\u00eda, Elena Hern\u00e1ndez, Vanessa N\u00fa\u00f1ez, Manuel Rodrigo, Miguel Gal\u00e1n (primer autor), I\u00f1aki Robles, Alberto Bengur\u00eda, David Sancho i Almudena Ramiro.<\/em><\/p>\n

No podem acabar aquesta entrevista sense respondre una pregunta clau: Guillermo, quin vincle creus que hi ha entre l\u2019art i la ci\u00e8ncia?\u00a0<\/b><\/p>\n

G: Jo crec que s\u2019uneixen en la idea de laboratori. Per a mi l\u2019estudi d\u2019un artista \u00e9s molt similar a un laboratori: en tots dos hi ha la cerca, l\u2019assaig, la prova i l\u2019error.\u00a0<\/span><\/p>\n

Curiosament, el Guillermo percep despla\u00e7ament en la imatge. El David tamb\u00e9 l\u2019hi veu, per\u00f2 des d\u2019una altra perspectiva: el despreniment de les plaques a les art\u00e8ries.<\/b> Aix\u00f2 \u00e9s el que passa quan art i ci\u00e8ncia s\u2019asseuen a mirar el mateix: cadascun hi aporta una forma nova i \u00fanica d\u2019entendre la realitat.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"<\/p>\n

Crear, observar, pensar, corregir, replantejar\u2026 Diries que aquests passos formen part del treball d\u2019un artista o d\u2019una recerca cient\u00edfica?<\/p>\n

Sense context \u00e9s dif\u00edcil triar, oi? Per\u00f2 si a l\u2019escena hi afegim pinzells i est\u00e0tues o, en canvi, pipetes o microscopis, la resposta potser sembla m\u00e9s evident. Aleshores, podr\u00edem dir que, en ess\u00e8ncia, art i ci\u00e8ncia s\u2019assemblen m\u00e9s del que pensem?<\/p>\n

\"\"<\/p>\n

En aquesta nova Instant\u00e0nia CaixaResearch ens hi acompanyen David Sancho<\/a>, investigador de la nostra xarxa al Centro Nacional de Investigaciones Cardiovasculares (CNIC), i Guillermo Mora<\/a>, artista visual i becari de la Fundaci\u00f3 \u201dla Caixa\u201d.<\/p>\n

Junts partirem d\u2019una imatge cient\u00edfica per explorar un descobriment biom\u00e8dic innovador i,<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[340],"tags":[],"class_list":["post-10677","post","type-post","status-publish","format-standard","hentry","category-sense-categoria"],"acf":[],"yoast_head":"\n\u201cDespla\u00e7ament\u201d - Blog CaixaCi\u00e8ncia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.caixaresearch.org\/ca\/instantania-caixaresearch-desplacament\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u201cDespla\u00e7ament\u201d - Blog CaixaCi\u00e8ncia\" \/>\n<meta property=\"og:description\" content=\"Crear, observar, pensar, corregir, replantejar\u2026 Diries que aquests passos formen part del treball d\u2019un artista o d\u2019una recerca cient\u00edfica? Sense context \u00e9s dif\u00edcil triar, oi? Per\u00f2 si a l\u2019escena hi afegim pinzells i est\u00e0tues o, en canvi, pipetes o microscopis, la resposta potser sembla m\u00e9s evident. Aleshores, podr\u00edem dir que, en ess\u00e8ncia, art i ci\u00e8ncia s\u2019assemblen m\u00e9s del que pensem? En aquesta nova Instant\u00e0nia CaixaResearch ens hi acompanyen David Sancho, investigador de la nostra xarxa al Centro Nacional de Investigaciones Cardiovasculares (CNIC), i Guillermo Mora, artista visual i becari de la Fundaci\u00f3 \u201dla Caixa\u201d. 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